| CAS NO: | 1228182-44-2 |
| 包装 | 价格(元) |
| 500μg | 电议 |
| 1mg | 电议 |
| 5mg | 电议 |
| Cas No. | 1228182-44-2 |
| 别名 | 西马特罗-D7; CL 263780-d7 |
| Canonical SMILES | NC1=CC=C(C(O)CNC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])C=C1C#N |
| 分子式 | C12H10D7N3O |
| 分子量 | 226.3 |
| 溶解度 | DMF: soluble,DMSO: soluble,Methanol: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Cimaterol-d7 is intended for use as an internal standard for the quantification of cimaterol by GC- or LC-MS. Cimaterol is a potent agonist of β-adrenergic receptors (pEC50 = 8.13, 8.78, and 6.62 for human β1, β2, and β3, respectively).1 Formulations containing cimaterol have been used in farmed animals (swine, fowl, etc.) to increase carcass mass and to alter muscle and fat deposition.2,3 |1. Mistry, S.N., Baker, J.G., Fischer, P.M., et al. Synthesis and in vitro and in vivo characterization of highly β1-selective β-adrenoceptor partial agonists. Journal of Medicinal Chemistry 56(10), 3852-3865 (2013).|2. Jones, R.W., Easter, R.A., McKeith, F.K., et al. Effect of the β-adrenergic agonist cimaterol (CL 263,780) on the growth and carcass characteristics of finishing swine. Journal of Animal Science 61(4), 905-913 (1985).|3. Byrem, T.M., Beermann, D.H., and Robinson, T.F. The β-agonist cimaterol directly enhances chronic protein accretion in skeletal muscle. Journal of Animal Science 76(4), 988-998 (1998). |
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