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Cimaterol-d7
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cimaterol-d7图片
CAS NO:1228182-44-2
包装与价格:
包装价格(元)
500μg电议
1mg电议
5mg电议

产品介绍
An internal standard for the quantification of cimaterol
Cas No.1228182-44-2
别名西马特罗-D7; CL 263780-d7
Canonical SMILESNC1=CC=C(C(O)CNC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])C=C1C#N
分子式C12H10D7N3O
分子量226.3
溶解度DMF: soluble,DMSO: soluble,Methanol: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Cimaterol-d7 is intended for use as an internal standard for the quantification of cimaterol by GC- or LC-MS. Cimaterol is a potent agonist of β-adrenergic receptors (pEC50 = 8.13, 8.78, and 6.62 for human β1, β2, and β3, respectively).1 Formulations containing cimaterol have been used in farmed animals (swine, fowl, etc.) to increase carcass mass and to alter muscle and fat deposition.2,3

|1. Mistry, S.N., Baker, J.G., Fischer, P.M., et al. Synthesis and in vitro and in vivo characterization of highly β1-selective β-adrenoceptor partial agonists. Journal of Medicinal Chemistry 56(10), 3852-3865 (2013).|2. Jones, R.W., Easter, R.A., McKeith, F.K., et al. Effect of the β-adrenergic agonist cimaterol (CL 263,780) on the growth and carcass characteristics of finishing swine. Journal of Animal Science 61(4), 905-913 (1985).|3. Byrem, T.M., Beermann, D.H., and Robinson, T.F. The β-agonist cimaterol directly enhances chronic protein accretion in skeletal muscle. Journal of Animal Science 76(4), 988-998 (1998).