Cl-4AS-1 是一种有效的甾体雄激素受体 (AR) 激动剂 (IC50 = 12 nM)，也是 5α-还原酶 I 型和 II 型的抑制剂（IC50 分别为 6 和 10 nM）。
| Cas No. | 188589-66-4 |
| 化学名 | (4aR,4bS,6aR,7S,9aS,9bS,Z)-N-(2-chlorophenyl)-1,4a,6a-trimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carbimidic acid |
| Canonical SMILES | C[C@@]12CC[C@@]3([H])[C@@]([C@]1([H])CC[C@]2([H])/C(O)=N/C4=CC=CC=C4Cl)([H])CCC(N5C)([H])[C@](C=CC5=O)3C |
| 分子式 | C26H33ClN2O2 |
| 分子量 | 441.01 |
| 溶解度 | <4.41mg/ml in ethanol;<4.41mg/ml in DMSO |
| 储存条件 | Store at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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