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RS 09(trifluoroacetate salt)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
RS 09(trifluoroacetate salt)图片
包装与价格：
包装价格(元)
500 µg电议
1mg电议
5mg电议
10mg电议

产品介绍
A TLR4 agonist
Canonical SMILESOC([C@H](CO)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC1=CN=CN1)NC([C@H]2N(C([C@H]3N(C([C@@H](N)C)=O)CCC3)=O)CCC2)=O)=O)=O)=O)=O.FC(F)(C(O)=O)F
分子式C31H49N9O9·XCF3COOH
分子量691.8
溶解度DMF: 1 mg/ml,DMSO: 10 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 1 mg/ml
储存条件Stored at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

RS 09 is a peptide agonist of toll-like receptor 4 (TLR4).1It activates NF-κB in a concentration-dependent manner in a secreted alkaline phosphatase (SEAP) assay using TLR4-expressing HEK293 cells and induces NF-κB nuclear translocation in the same cells. It also induces cytokine secretion from RAW 264.7 cells. RS 09 (25 µg/animal) acts as an adjuvant in mice vaccinated with a KLH-conjugated X-15 antigen, with no antibodies produced in mice receiving RS 09 without the antigen.

1.Shanmugam, A., Rajoria, S., George, A.L., et al.Synthetic toll like receptor-4 (TLR-4) agonist peptides as a novel class of adjuvantsPLoS One7(2)e30839(2012)