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CGP 36742
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CGP 36742图片
CAS NO:123690-78-8
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
CGP 36742 是一种选择性 GABAB 受体拮抗剂,可在外周给药后穿透血脑屏障,IC50 为 32 μM。CGP 36742 可用于治疗抑郁症。
Cas No.123690-78-8
别名SGS-742
Canonical SMILESO=P(CCCN)(O)CCCC
分子式C7H18NO2P
分子量179.2
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CGP 36742 is a selective GABAB receptor antagonist that can penetrate the blood-brain barrier after peripheral administration, with an IC50 of 32 μM. CGP 36742 is useful in treatment of depression[1]. IC50: 32 μM (GABAB)[1]

[1]. Nowak G, et al. Antidepressant-like activity of CGP 36742 and CGP 51176, selective GABAB receptor antagonists, in rodents. Br J Pharmacol. 2006 Nov;149(5):581-90.