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(Z)-Capsaicin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(Z)-Capsaicin图片
CAS NO:25775-90-0
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议
50mg电议

产品介绍
(Z)-Capsaicin 是 capsaicin 的顺式异构体,为可口服的 TRPV1 激动剂,可用于神经性疼痛的研究。
Cas No.25775-90-0
别名(Z)-辣椒素; Zucapsaicin; Civamide; cis-Capsaicin
Canonical SMILESCC(C)/C=C\CCCCC(NCC1=CC=C(O)C(OC)=C1)=O
分子式C18H27NO3
分子量305.41
溶解度DMSO: ≥ 125 mg/mL (409.29 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(Z)-Capsaicin is the cis isomer of capsaicin, acts as an orally active TRPV1 agonist, and is used in the research of neuropathic pain. TRPV1 receptor[1]

(Z)-Capsaicin is the cis isomer of capsaicin, acting as a TRPV1 agonist. (Z)-Capsaicin may also blocks the neruonal calcium channel[1].

(Z)-Capsaicin (Zucapsaicin) significantly attenuates nociceptive behavior after oral administration in rats. (Z)-Capsaicin is also tolerated in the primary or recurrent experimental genital herpes simplex virus infection in guinea pigs[1].

[1]. Bourne N, et al. Civamide (cis-capsaicin) for treatment of primary or recurrent experimental genital herpes. Antimicrob Agents Chemother. 1999 Nov;43(11):2685-8.