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(S)-(-)-5-Fluorowillardiine hydrochloride
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(S)-(-)-5-Fluorowillardiine hydrochloride图片
CAS NO:1321546-70-6
包装与价格：
包装价格(元)
10mM (in 1mL Water)电议
50mg电议
100mg电议
200mg电议

产品介绍
(S)-(-)-5-Fluorowillardiine hydrochloride 是AMPAR高效选择性激动剂。
Cas No.1321546-70-6
别名(5S)-Fluorowillardiine hydrochloride; (S)-5-Fluorowillardiine hydrochloride
Canonical SMILESOC([C@@H](N)CN1C=C(F)C(NC1=O)=O)=O.[H]Cl
分子式C7H9ClFN3O4
分子量253.62
溶解度Water: 6.67 mg/mL (26.30 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(S)-(-)-5-Fluorowillardiine hydrochloride is a potent and specific AMPAR agonist.

[1]. Hawkinson JE, et al. Effects of thiocyanate and AMPA receptor ligands on (S)-5-fluorowillardiine, (S)-AMPA and (R,S)-AMPA binding. Eur J Pharmacol. 1997 Jun 25;329(2-3):213-21. [2]. Kessler M, et al. Use of [3H]fluorowillardiine to study properties of AMPA receptor allosteric modulators. Brain Res. 2006 Mar 3;1076(1):25-41. [3]. Rembach A, et al. Antisense peptide nucleic acid targeting GluR3 delays disease onset and progression in the SOD1 G93A mouse model of familial ALS. J Neurosci Res. 2004 Aug 15;77(4):573-82.