包装 | 价格(元) |
50mg | 电议 |
100mg | 电议 |
500mg | 电议 |
分子式 | C38H73NO8 |
分子量 | 2706.38 |
溶解度 | DMSO : 100 mg/mL (36.95 mM; Need ultrasonic) |
储存条件 | Store at -20°C, stored under nitrogen |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | PEG2000-C-DMG, a lipid, can be used for the preparation of Onpattro. Onpattro, a hepatically directed investigational RNAi therapeutic agent, harnesses this process to reduce the production of mutant and wild-type transthyretin by targeting the 3′ untranslated region of transthyretin mRNA[1][2]. [1]. Garber K. Alnylam launches era of RNAi drugs. Nat Biotechnol. 2018;36(9):777-778. [2]. Adams D, Gonzalez-Duarte A, O’Riordan WD, et al. Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis. N Engl J Med. 2018;379(1):11-21. |