您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Reproxalap
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Reproxalap
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Reproxalap图片
CAS NO:916056-79-6
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
Reproxalap (ADX-102) 是一种研究干眼症的活性醛类隔离剂。Reproxalap 与醛 (包括丙二醛和 4-羟基壬醛) 共价结合。
Cas No.916056-79-6
别名ADX-102; NS-2
分子式C12H13ClN2O
分子量236.7
溶解度DMSO : 100 mg/mL (422.48 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Reproxalap (ADX-102) is a reactive aldehyde species (RASP) sequestering agent for the treatment of dry eye. Reproxalap (ADX-102) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal[1][2].

[1]. Susan Macdonald, et al. ADX-102, a novel aldehyde trap, reduces nociceptive behavior in mouse models of carrageenan and CFA induced pain.
[2]. Reproxalap Phase 2b Dry Eye Disease Results.