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S1QEL1,1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
S1QEL1,1图片
CAS NO:897613-29-5
包装与价格:
包装价格(元)
500μg电议
1mg电议
5mg电议
10mg电议

产品介绍
Cas No.897613-29-5
Canonical SMILESCC(NC1=CC=CC(NC(C(NCCC2=C(C)N=C(C3=CC=C(C)C=C3)S2)=O)=O)=C1)=O
分子式C23H24N4O3S
分子量436.5
溶解度DMF: 3 mg/ml,DMF:PBS(pH7.2) (1:2): 0.33 mg/ml,DMSO: 2 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

S1QEL1.1 is a small molecule that suppresses superoxide production during reverse electron transport through the IQ site of the mitochondrial respiratory complex I (IC50 = 70 nM) without affecting oxidative phosphorylation. It diminishes endogenous oxidative damage in primary astrocytes, reduces stress-induced signaling in a cardiomyocyte cell model, and protects against ischemia-reperfusion injury in perfused mouse heart.