CAS NO: | 1219386-75-0 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
Cas No. | 1219386-75-0 |
别名 | DL-肉碱盐酸盐-D9氘代,DL-Carnitine-d9 chloride |
Canonical SMILES | OC(CC(O)C[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O.[Cl-] |
分子式 | C7H7D9NO3.Cl |
分子量 | 206.7 |
溶解度 | DMF: 15 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 10 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | DL-Carnitine-d9is intended for use as an internal standard for the quantification of carnitine by GC- or LC-MS. DL-Carnitine is a racemic mixture of L- and D-carnitine. Unlike L-carnitine, DL-carnitine (60 and 120 µM) does not increase glucose or urea production from L-glutamine in isolated rat liver and does not compensate for carnitine deficiency in the skeletal muscle of rats receiving a carnitine-deficient diet.1,2DL-Carnitine induces tetanic fade in stimulated isolated rat phrenic nerve diaphragm preparations when used at a concentration of 60 µM, an effect that can be blocked by choline.3 1.Lopes, G., Gazola, V.A., Galende, S.B., et al.Comparative acute effects of l-carnitine and dl-carnitine on hepatic catabolism of l-alanine and l-glutamine in ratsActa Pharmacol. Sin.25(10)1257-1261(2004) 2.Spasov, A.A., Iezhitsa, I.N., Kravchenko, M.S., et al.Effects of L-, D-, and DL-carnitine on morphometric parameters of skeletal muscle and exercise performance of laboratory animals receiving carnitine-deficient dietBull. Exp. Biol. Med.142(4)458-460(2006) 3.Lopes, G., Bazotte, R.B., Curi, R., et al.L- and DL-carnitine induce tetanic fade in rat neuromuscular preparationBraz. J. Med. Biol. Res.36(9)1255-1262(2003) |