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Incensole Acetate
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Incensole Acetate图片
CAS NO:34701-53-6
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
Incensole acetate是卡氏乳香树脂的主要成分，对创伤性和缺血性颅脑损伤中的神经元损伤具有神经保护作用。Incensole acetate 减少了 hOBNSC 中由 Aβ 25-35 触发的细胞凋亡(apoptosis)。
Cas No.34701-53-6
别名因香酚乙酸酯
Canonical SMILESCC([C@@]12C/C=C(C)/CC/C=C(C)/CC[C@H](OC(C)=O)[C@@](O2)(C)CC1)C
分子式C22H36O3
分子量348.52
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Incensole acetate is a main constituent of Boswellia carterii resin, has neuroprotective effects against neuronal damage in traumatic and ischemic head injury. Incensole acetate reduces Aβ25-35-triggered apoptosis in hOBNSCs[1].

Incensole acetate (100 μM; pre-treatment 4 hours) significantly ameliorates Aβ 25-35-induced cell death, a 48-52% decrease in cell viability at Aβ25-35 is restored to 85-89% upon pre-treatment with IA[1].Incensole acetate (5-100 μM) pretreatment reverses increase in the mRNA and protein level of Bax, caspase 8, cyto c and decrease in the mRNA and protein level of Bcl2 induced by Aβ 25-35 in hOBNSCs[1]. Cell Viability Assay[1] Cell Line: Human olfactory bulb neural stem cells

[1]. El-Magd MA, et al. Incensole acetate prevents beta-amyloid-induced neurotoxicity in human olfactory bulb neural stem cells. Biomed Pharmacother. 2018 Sep;105:813-823.