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SR-4370
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SR-4370图片
CAS NO:1816294-67-3
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
SR-4370 是一种 HDAC 抑制剂,对 HDAC1、HDAC2、HDAC3、HDAC8 和 HDAC6 的 IC50 值分别为 0.13 μM、0.58 μM、0.006 μM、2.3 μM 和 3.4 μM。
Cas No.1816294-67-3
Canonical SMILESO=C(C1=CC=C(C2=CC=CC(F)=C2F)C=C1)NNCCCC
分子式C17H18F2N2O
分子量304.33
溶解度DMSO : ≥ 150 mg/mL (492.89 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

SR-4370 is an inhibitor of HDAC, with IC50s of 0.13 uM, 0.58 uM, 0.006 uM, 2.3 uM, and 3.4 uM for HDAC1, HDAC2, HDAC3, HDAC8, and HDAC6, respectively.

SR-4370 is an inhibitor of HDAC, with IC50s of 0.13 uM, 0.58 uM, 0.006 uM, 2.3 uM, and 3.4 uM for HDAC1, HDAC2, HDAC3, HDAC8, and HDAC6, respectively. SR-4370 is cytotoxic to the breast cancer cells (MDA-MB-231), with an IC50 of 12.6 uM[1].

References:
[1]. LIAO, Daiqing, et al. HDAC INHIBITOR COMPOUNDS AND METHODS OF TREATMENT. WO 2015153516 A1.