您好，欢迎来到化工原料网！ [登录] [免费注册]
化工原料网
发布求购
位置：首页 > 产品库 > Eicosapentaenoyl Ethanolamide-d4
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
Eicosapentaenoyl Ethanolamide-d4
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Eicosapentaenoyl Ethanolamide-d4图片
CAS NO:946524-41-0
包装与价格：
包装价格(元)
100 μg电议
500 μg电议
1mg电议
5mg电议

产品介绍
An internal standard for the quantification of EPEA
Cas No.946524-41-0
Canonical SMILESO=C(NC([2H])([2H])C([2H])([2H])O)CCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC
分子式C22H31D4NO2
分子量349.5
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Eicosapentaenoyl ethanolamide (EPEA)-d4contains four deuterium atoms at the 1, 1', 2, and 2' positions. It is intended for use as an internal standard for the quantification of EPEA by GC-or LC-mass spectrometry. Eicosapentaenoyl Ethanolamide (EPEA) is an N-acylethanolamide that inhibits dietary-restriction-induced lifespan extension in wild type and TOR pathway mutant nematodes.1Produced endogenously from eicosapentaenoic acid, EPEA serves as a metabolic signal that couples nutrient availability with growth and lifespan. EPEA also has anti-inflammatory properties, suppressing the expression of IL-6 and MCP-1 in 3T3-L1 adipocytes in response to lipopolysaccharide.2

1.Lucanic, M., Held, J.M., Vantipalli, M.C., et al.N-acylethanolamine signalling mediates the effect of diet on lifespan in Caenorhabditis elegansNature473(7346)226-229(2011) 2.Balvers, M.G., Verhoeckx, K.C., Plastina, P., et al.Docosahexaenoic acid and eicosapentaenoic acid are converted by 3T3-L1 adipocytes to N-acyl ethanolamines with anti-inflammatory propertiesBiochimica et Biophysica Acta1801(10)1107-1114(2010)