| 包装 | 价格(元) |
| 10mM (in 1mL DMSO) | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| Canonical SMILES | FC1=CC=CC(/C=C/C2=CC(NC(N)=C3C#N)=C3C=C2)=C1 |
| 分子式 | C17H12FN3 |
| 分子量 | 277.3 |
| 溶解度 | DMSO : ≥ 125 mg/mL (450.78 mM);Water :< 0.1 mg/mL (insoluble) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor, with an IC50 of 160 nM for USP20/Ub-Rho. [1]. "Harrigan JA, et al.Deubiquitylating enzymes and drug discovery: emerging opportunities.Nat Rev Drug Discov. 2018 Jan;17(1):57-78." [2]. Nishi Kumari, et al. Targeting the Ubiquitin Proteasome System in Cancer |
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