您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > 12-Bromododecanoic Acid
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
12-Bromododecanoic Acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
12-Bromododecanoic Acid图片
CAS NO:73367-80-3
包装与价格:
包装价格(元)
250mg电议
500mg电议
1 g电议

产品介绍
A halogenated form of lauric acid
Cas No.73367-80-3
别名12-溴十二烷酸
Canonical SMILESBrCCCCCCCCCCCC(O)=O
分子式C12H23BrO2
分子量279.2
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

12-Bromododecanoic acid is a halogenated form of lauric acid . It has been used in the synthesis of clickable forms of myristic acid and as a model fatty acid ligand to determine the X-ray crystal structure of bovine β-lactoglobulin-ligand complexes.1,212-Bromododecanoic acid (10 µg/ml) reduces virion DNA in the culture supernatant of primary hepatocytes isolated from a duckling model of hepatitis B virus (HBV) infection and inhibits HIV replication in CEM-SS T cells (EC50= 38 µM).3

1.Heal, W.P., Wickramasinghe, S.R., Leatherbarrow, R.J., et al.N-Myristoyl transferase-mediated protein labelling in vivoOrg. Biomol. Chem.6(13)2308-2315(2008) 2.Qin, B.Y., Creamer, L.K., Baker, E.N., et al.12-Bromododecanoic acid binds inside the calyx of bovine β-lactoglobulinFEBS Lett.438(3)272-278(1998) 3.Parang, K., Wiebe, L.I., Knaus, E.E., et al.In vitro antiviral activities of myristic acid analogs against human immunodeficiency and hepatitis B virusesAntiviral Res.34(3)75-90(1997)