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(-)-G-Lactone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(-)-G-Lactone图片
CAS NO:43119-28-4
包装与价格:
包装价格(元)
250mg电议
500mg电议
1 g电议
5 g电议

产品介绍
A bicyclic γ-lactone
Cas No.43119-28-4
别名(1S,5R)-2-氧杂二环[3.3.0]辛-6-烯-3-酮
Canonical SMILESO=C1C[C@@]2([H])[C@@](CC=C2)([H])O1
分子式C7H8O2
分子量124.1
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml,Ethanol: 15 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(-)-G-lactone is a bicyclic γ-lactone prostaglandin chiral synthon and a building block.1,2It is a prostaglandin chiral synthon formed from an asymmetric Baeyer-Villiger oxidation reaction.1(-)-G-lactone has also been used as a building block in the synthesis of HIV-1 protease inhibitors.2

1.Alphand, V., Archelas, A., and Furstoss, R.Microbial Transformations 16. One-step synthesis of a pivotal prostaglandin chiral synthon via a highly enantioselective microbiological Baeyer-Villiger type reactionTetrahedron Lett.30(28)3663-3664(1989) 2.Ghosh, A.K., Chapsal, B.D., Baldridge, A., et al.Design and synthesis of potent HIV-1 protease inhibitors incorporating hexahydrofuropyranol-derived high affinity P2 ligands: Structure-activity studies and biological evaluationJ. Med. Chem.54(2)622-634(2011)