| CAS NO: | 43119-28-4 |
| 包装 | 价格(元) |
| 250mg | 电议 |
| 500mg | 电议 |
| 1 g | 电议 |
| 5 g | 电议 |
| Cas No. | 43119-28-4 |
| 别名 | (1S,5R)-2-氧杂二环[3.3.0]辛-6-烯-3-酮 |
| Canonical SMILES | O=C1C[C@@]2([H])[C@@](CC=C2)([H])O1 |
| 分子式 | C7H8O2 |
| 分子量 | 124.1 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml,Ethanol: 15 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | (-)-G-lactone is a bicyclic γ-lactone prostaglandin chiral synthon and a building block.1,2It is a prostaglandin chiral synthon formed from an asymmetric Baeyer-Villiger oxidation reaction.1(-)-G-lactone has also been used as a building block in the synthesis of HIV-1 protease inhibitors.2 1.Alphand, V., Archelas, A., and Furstoss, R.Microbial Transformations 16. One-step synthesis of a pivotal prostaglandin chiral synthon via a highly enantioselective microbiological Baeyer-Villiger type reactionTetrahedron Lett.30(28)3663-3664(1989) 2.Ghosh, A.K., Chapsal, B.D., Baldridge, A., et al.Design and synthesis of potent HIV-1 protease inhibitors incorporating hexahydrofuropyranol-derived high affinity P2 ligands: Structure-activity studies and biological evaluationJ. Med. Chem.54(2)622-634(2011) |
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