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Sapienic acid sodium
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sapienic acid sodium图片
CAS NO:217477-25-3
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Sapienicacidsodium是一种常见于皮肤和粘膜中的脂肪酸,对皮肤和口腔中发现的革兰氏阳性和革兰氏阴性细菌具有可变的抗菌活性。Sapienicacidsodium对血链球菌,微生物链球菌和核纤梭菌具有活性,其MBC值分别为31.3μg/mL,375.0μg/mL和93.8μg/mL。
Cas No.217477-25-3
Canonical SMILESCCCCCCCCC/C=C\CCCCC(O[Na])=O
分子式C16H29NaO2
分子量276.39
溶解度Methanol: 250 mg/mL (904.52 mM); Ethanol: 33.33 mg/mL (120.59 mM)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Sapienic acid sodium is a fatty acid commonly found on the skin and in mucosa. Sapienic acid sodium has variable antimicrobial activities against Gram-positive and Gram-negative bacteria found on the skin and in the oral cavity. Sapienic acid sodium is active against Streptococcus sanguinis, Streptococcus mitis and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively[1].

Sapienic acid (minimum bactericidal concentrations (MBCs) range, 31.3 to 375.0 μg/mL) is active against Streptococcus sanguinis, Streptococcus mitis, and Fusobacterium nucleatum but not active against Escherichia coli, Staphylococcus aureus, S. marcescens, P. aeruginosa, Corynebacterium bovis, Corynebacterium striatum, and Corynebacterium jeikeium (MBC >500 μg/mL). Kinetic assays show that killing of S. sanguinis and S. mitis with sapienic acid is gradual and occurred within 24 h[1].

[1]. Fischer CL, et al. Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria. Antimicrob Agents Chemother. 2012 Mar;56(3):1157-61.