您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Estrone
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Estrone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Estrone图片
CAS NO:53-16-7
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
雌酮(E1)是一种天然雌激素。
Cas No.53-16-7
别名雌酮; E1; Oestrone
化学名(8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
Canonical SMILESCC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)O
分子式C18H22O2
分子量270.37
溶解度≥ 9.75 mg/mL in DMSO, ≥ 9.2 mg/mL in EtOH with ultrasonic and warming
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Estrone is an estrogenic hormone.Target: Estrogen Receptor/ERREstrone (E1) is an estrogenic hormone secreted by the ovary as well as adipose tissue with the chemical name of 3-hydroxyestra-1,3,5(10)-triene-17-one and the chemical formula C18H22O2. Estrone is one of several natural estrogens, which also include estriol and estradiol. Estrone is the least abundant of the three hormones; estradiol is present almost always in the reproductive female body, and estriol is abundant primarily during pregnancy. Estrone is relevant to health and disease states because of its conversion to estrone sulfate, a long-lived derivative. Estrone sulfate acts as a reservoir that can be converted as needed to the more active estradiol. It is the predominant estrogen in postmenopausal women [1, 2].

References:
[1]. Hoffmann, B., et al., [Profiles of estrone, estrone sulfate and progesterone in donkey (Equus asinus) mares during pregnancy]. Tierarztl Prax Ausg G Grosstiere Nutztiere, 2014. 42(1): p. 32-9.
[2]. Oneson, I.B. and S.L. Cohen, The nature of the conjugated estrone in human pregnancy urine. Endocrinology, 1952. 51(3): p. 173-82.