Cas No. | 110429-36-2 |
别名 | 甲基帕罗西汀 |
Canonical SMILES | FC1=CC=C([C@H]2[C@H](COC3=CC(OCO4)=C4C=C3)CN(C)CC2)C=C1 |
分子式 | C20H22FNO3 |
分子量 | 343.4 |
溶解度 | DMF: 33 mg/ml,DMF:PBS (pH 7) (1:10): 0.09 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | N-methyl Paroxetine is a derivative of the selective serotonin reuptake inhibitor (SSRI) antidepressant paroxetine that inhibits [3H]paroxetine binding to rat cortical membranes (Ki = 4.3 nM). It inhibits serotonin uptake in rat brain synaptosomes with an IC50 value of 22 nM. N-methyl Paroxetine has been used as a precursor in the synthesis of paroxetine and is a potential impurity in commercial preparations of paroxetine. |