Lumichrome 是核黄素的光降解产物，是人类的内源性化合物。 Lumichrome 通过 p53 依赖性机制抑制人肺癌细胞生长并诱导细胞凋亡。
| Cas No. | 1086-80-2 |
| 别名 | 光色素 |
| Canonical SMILES | CC1=C(C)C=C(NC(C2=N3)=NC(NC2=O)=O)C3=C1 |
| 分子式 | C12H10N4O2 |
| 分子量 | 242.2 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Lumichrome is a natural metabolite of riboflavin. It can be made by photolysis of riboflavin or it can be produced enzymatically in certain microbes and plants. Lumichrome produced by Rhizobium and other bacterial species induces major developmental changes in plants at nanomolar concentrations. Lumichrome can stimulate larval metamorphosis in ascidians and activate the LasR quorum sensing receptor of bacteria. Lumichrome competitively inhibits the uptake of riboflavin by riboflavin transporters from prokaryotes and eukaryotes. |
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