| CAS NO: | 15533-09-2 |
| 包装 | 价格(元) |
| 500μg | 电议 |
| 1mg | 电议 |
| 5mg | 电议 |
| Cas No. | 15533-09-2 |
| Canonical SMILES | OC1=C(/C(C)=N/NC(C2=C(O)C=CC=C2)=O)C=CC=C1 |
| 分子式 | C15H14N2O3 |
| 分子量 | 270.3 |
| 溶解度 | DMF: 1 mg/ml,DMF:PBS(pH 7.2)(1:6): 0.14 mg/ml,DMSO: 1 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Compound C108 is an inhibitor of the GTPase-activating protein (SH3 domain)-binding protein 2 (G3BP2), which is involved in breast tumor initiation. In a mouse xenograft model of breast cancer, compound C108 (1 µM for 24 hours) reduces the proportion of tumor-initiating cells approximately 10-fold compared with untreated cells. In MDA-MB-453 cells, and in the patient-derived xenograft cell line MAXF 401, it diminishes mammosphere formation. |
m.cnreagent.com