包装: | 1mg |
市场价: | 5730元 |
Canonical SMILES | BrC1=NC2=C(N1[C@]3([H])O[C@@]4([H])[C@@H](O)[C@H]3O)N=CN([C@@]5([H])[C@H](O)[C@H](O)[C@](COP(OP(OC4)(O)=O)(O)=O)([H])O5)C2=N.[Na+].[Na+] |
分子式 | C15H20BrN5O13P2•2Na |
分子量 | 666.2 |
溶解度 | Water: Soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Cyclic ADP-ribose (cADP-ribose) is a calcium mobilizing nucleotide that is biosynthesized from NAD+ by cADP-ribose synthases, including CD38. cADP-Ribose appears to activate calcium channels in intracellular membranes, which in turn activate ryanodine receptors. 8-bromo-cADP-Ribose is a stable, cell-permeable analog that blocks calcium release evoked by cADP-ribose in sea urchin egg homogenates with an IC50 value of 1.7 µM. It is commonly used to investigate intracellular signaling through cADP-ribose in isolated cells and tissues. |