Mal-PEG2-Val-Cit-amido-PAB-OH

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2055041-38-6

包装与价格：

产品介绍

Mal-PEG2-Val-Cit-amido-PAB-OH 是一种可降解 (cleavable) 的 ADC linker，用于抗体偶联药物 (ADCs) 的合成。 Mal-PEG2-Val-Cit-amido-PAB-OH 也可用作 PROTAC 的 Linker，可用于 PROTAC 的合成。

Cas No.	2055041-38-6
分子式	C₂₉H₄₂N₆O₉
分子量	618.68
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Mal-PEG2-Val-Cit-amido-PAB-OH is a cleavableADC linkerused in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-Val-Cit-amido-PAB-OH also can be used as aPROTAC linkerthat can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.