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Byakangelicol
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Byakangelicol图片
CAS NO:26091-79-2
包装:20mg
市场价:3192元

产品介绍
Byakangelicol 是从白芷中分离出来的，通过抑制 cyclooxygenase-2 (COX-2) 的表达和 COX-2 酶的活性来抑制 A549 细胞中白细胞介素 1beta (IL-1beta) 诱导的前列腺素 E2 (PGE2) 释放。
Cas No.26091-79-2
别名白当归脑
化学名9-[[(2R)-3,3-dimethyloxiran-2-yl]methoxy]-4-methoxyfuro[3,2-g]chromen-7-one
Canonical SMILESCC1(C(O1)COC2=C3C(=C(C4=C2OC(=O)C=C4)OC)C=CO3)C
分子式C17H16O6
分子量316.09
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Byakangelicol, isolated from Angelica dahurica, inhibits interleukin-1beta (IL-1beta) -induced prostaglandin E2 (PGE2) release in A549 cells mediated by suppression of cyclooxygenase-2 (COX-2) expression and the activity of COX-2 enzyme. Byakangelicol has therapeutic potential as an anti-inflammatory drug on airway inflammation[1].

References:
[1]. Lin CH, et al. Byakangelicol, isolated from Angelica dahurica, inhibits both the activity and induction of cyclooxygenase-2 in human pulmonary epithelial cells. J Pharm Pharmacol. 2002 Sep;54(9):1271-8.