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15(S)-HETE-d8
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
15(S)-HETE-d8图片
CAS NO:84807-87-4
包装与价格：
包装价格(元)
25 μg电议
50 μg电议
100 μg电议

产品介绍
An internal standard for the quantification of 15-HETE
Cas No.84807-87-4
Canonical SMILESCCCCC[C@]([2H])(O)/C([2H])=C/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCC(O)=O
分子式C20H24D8O3
分子量328.5
溶解度0.1 M Na2CO3: 2 mg/ml,DMF: Miscible,DMSO: Miscible,Ethanol: Miscible,PBS pH 7.2: 0.8 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

15(S)-HETE-d8contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of 15(S)-HETE by GC-or LC-MS. 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes.115(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis.2

1.Nadel, J.A., Conrad, D.J., Ueki, I.F., et al.Immunocytochemical localization of arachidonate 15-lipoxygenase in erythrocyes, leukocytes, and airway cellsJournal of Clinical Investigation871139-1145(1991) 2.Ramis, I., RosellÓ-Catafau, J., Bulbena, O., et al.15-Hydroxyeicosatetraenoic acid as a major eicosanoid in nasal secretions: Assay by high-performance liquid chromatographic-radioimmunoassay and gas chromatographic-mass spectrometric proceduresJournal of Chromatography496416-422(1989)