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Trimethoprim N-oxide
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Trimethoprim N-oxide图片
CAS NO:27653-68-5
包装:1mg
市场价:1260元

产品介绍
TrimethoprimN-oxide(Trimethoprim1-N-oxide)属于人尿代谢物。TrimethoprimN-oxide是通过氧化嘧啶环中的氮原子生成的。TrimethoprimN-oxide主要由CYP1A2在人肝微粒体中形成。
Cas No.27653-68-5
别名Trimethoprim 1-N-oxide
Canonical SMILESNC1=NC(N)=C(CC2=CC(OC)=C(OC)C(OC)=C2)C=[N+]1[O-]
分子式C14H18N4O4
分子量306.32
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Trimethoprim N-oxide (Trimethoprim 1-N-oxide) belongs to human urinary metabolites. Trimethoprim N-oxide is generated by oxidation of nitrogen atoms in the pyrimidine ring. Trimethoprim N-oxide is formed predominantly by CYP1A2 in human liver microsomes[1].

[1]. Goldman JL, et al. In Vitro Hepatic Oxidative Biotransformation of Trimethoprim. Drug Metab Dispos. 2015 Sep;43(9):1372-80.