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RIPK-IN-4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
RIPK-IN-4图片
CAS NO:2141969-56-2
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
RIPK-IN-4 是一种有效选择性的、具有良好的口服生物利用度的 RIPK2 抑制剂,IC50 值为 3 nM。
Cas No.2141969-56-2
Canonical SMILESO=S(C1=CN2C(C3=CC(N)=NC(F)=C3)=CN=C2C=C1OCC)(C(C)(C)C)=O
分子式C18H21FN4O3S
分子量392.45
溶解度DMSO: 31.25 mg/mL (79.63 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

RIPK-IN-4 is a potent and selective RIPK2 inhibitor with excellent oral bioavailability, and has an IC50 of 3 nM[1]. IC50: 3 nM (RIPK2)[1]

[1]. He X, et al. Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases. ACS Med Chem Lett. 2017 Sep 27;8(10):1048-1053.