您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Pimpinellin
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Pimpinellin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pimpinellin图片
CAS NO:131-12-4
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Pimpinellin 是 Cyrtomium fortumei (J.) 的一种成分。Pimpinellin 通过诱导肿瘤细胞凋亡 (apoptosis) 抑制肿瘤细胞的生长。
Cas No.131-12-4
别名茴芹内酯
Canonical SMILESO=C(C=C1)OC2=C1C(OC)=C(OC)C3=C2C=CO3
分子式C13H10O5
分子量246.22
溶解度Soluble in DMSO
储存条件-20°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Pimpinellin is a constituent of Cyrtomium fortumei (J.). Pimpinellin inhibits the growth of tumor cells via the induction of tumor cell apoptosis[1].

Pimpinellin has potent cytotoxic activities against the three tumor cells MGC-803, PC3, and A375, with the IC50 values of 14.4±0.3 μM, 20.4±0.5 μM, and 29.2±0.6 μM, respectively. Pimpinellin inhibits the growth of MGC-803 cells via the induction of tumor cell apoptosis, with apoptosis ratio of 27.44% after 72 h of treatment at 20 μM[1].

[1]. Yang S, et al. Discovery and antitumor activities of constituents from Cyrtomium fortumei (J.) Smith rhizomes. Chem Cent J. 2013 Feb 4;7(1):24.