CAS NO: | 939983-14-9 |
包装 | 价格(元) |
10mg | 电议 |
100mg | 电议 |
Cas No. | 939983-14-9 |
别名 | REL-2-[4-[[(4R,5S)-4,5-双(4-氯苯基)-2-[4-(1,1-二甲基乙基)-2-乙氧基苯基]-4,5-二氢-4,5-二甲基-1H-咪唑-1-基]羰基]-1-哌嗪基]-1-(4-吗啉基)乙酮 |
Canonical SMILES | O=C(N1C(C2=CC=C(C=C2OCC)C(C)(C)C)=N[C@](C)([C@]1(C3=CC=C(Cl)C=C3)C)C4=CC=C(C=C4)Cl)N5CCN(CC5)CC(N6CCOCC6)=O.[relative stereochemistry] |
分子式 | C40H49Cl2N5O4 |
分子量 | 734.75 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | p53 and MDM2 proteins-interaction-inhibitor (racemic) (Compound 2j) is an inhibitor of the interaction between p53 and MDM2 proteins. [1]. Vu B, et al. Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical Development. ACS Med Chem Lett. 2013 Apr 2;4(5):466-9. |