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MARK4 inhibitor 1
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
MARK4 inhibitor 1图片
CAS NO:2271081-58-2
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
50mg电议

产品介绍
MARK4 inhibitor 1 是有效的 MARK4 的抑制剂，IC50 值为1.54 μM。MARK4 inhibitor 1抑制癌细胞增殖、转移，诱导凋亡。
Cas No.2271081-58-2
Canonical SMILESCOC1=CC=C(CN2N=NC(C(N/N=C3C(NC4=C\3C=CC=C4C)=O)=O)=C2)C=C1
分子式C20H18N6O3
分子量390.4
溶解度DMSO: 5 mg/mL (12.81 mM; ultrasonic and adjust pH to 2 with HCl)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM. MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis[1]. IC50: 1.54 μM (MARK4)[1].

[1]. Aneja B, et al. Design and development of Isatin-triazole hydrazones as potential inhibitors of microtubule affinity-regulating kinase 4 for the therapeutic management of cell proliferation and metastasis. Eur J Med Chem. 2019 Feb 1;163:840-852.