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4-Hydroxyderricin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
4-Hydroxyderricin图片
CAS NO:55912-03-3
包装:5mg
市场价:1800元

产品介绍
4-Hydroxyderricin是当归的主要活性成分之一,是一种有效的,选择性MAO-B(单胺氧化酶抑制剂)抑制剂,IC50为3.43μM。4-Hydroxyderricin可以轻度抑制DBH(多巴胺β-羟化酶)活性。4-Hydroxyderricin具有抗抑郁活性。
Cas No.55912-03-3
别名4-羟基德里辛
Canonical SMILESO=C(C1=CC=C(OC)C(C/C=C(C)\C)=C1O)/C=C/C2=CC=C(O)C=C2
分子式C21H22O4
分子量338.4
储存条件4℃, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

4-Hydroxyderricin, the major active ingredients of Angelica keiskei Koidzumi, is a potent selective MAO-B (Monoamine oxidase inhibitors) inhibitor with an IC50 of 3.43 μM. 4-Hydroxyderricin also mildly inhibits DBH (dopamine β-hydroxylase) activity. 4-Hydroxyderricin has antidepressant activity[1].

[1]. Kim JH, et al. Xanthoangelol and 4-Hydroxyderricin Are the Major Active Principles of the Inhibitory Activities against Monoamine Oxidases on Angelica keiskei K. Biomol Ther (Seoul). 2013 May 30;21(3):234-40.