您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Mephenytoin
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Mephenytoin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mephenytoin图片
CAS NO:50-12-4
包装:10mg
市场价:1350元

产品介绍
Mephenytoin 是一种抗惊厥药,是 CYP2C19 和 CYP2B6 的底物。
Cas No.50-12-4
别名美芬妥因
Canonical SMILESO=C1C(C2=CC=CC=C2)(CC)NC(N1C)=O
分子式C12H14N2O2
分子量218.25
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CYP2C19 and CYP2B6 substrate. Anticonvulsant.

Knabe and Wunn (1980) Racemic and optically active hydantoins from disubstituted cyanoacetic acids. Arch.Pharmacol. 313 53 |Foti et al (2008) CYP2C19 inhibition: the impact of substrate probe selection on in vitro inhibition profiles. Drug Meta. Dispos. 36 523 PMID:18048485 |Tamminga et al (2001) Mephenytoin as a probe for CYP2C19 phenotyping: effect of sample storage, intra-individual reproducibility and occurrence of adverse events. Br.J.Clin.Pharmacol. 51 471 PMID:11422005