HDS 029 (compound 29) 是一种有效的酪氨酸激酶抑制剂，对 erbB1、erbB2、erbB4、EGF、HER 的 IC50 分别为 0.3、1.1、0.5、2.5、24 nM。
| Cas No. | 881001-19-0 |
| 化学名 | N-(4-((3-chloro-4-fluorophenyl)amino)pyrido[3,4-d]pyrimidin-6-yl)but-2-ynamide |
| Canonical SMILES | ClC1=CC(NC2=NC=NC3=C2C=C(NC(C#CC)=O)N=C3)=CC=C1F |
| 分子式 | C17H11ClFN5O |
| 分子量 | 355.76 |
| 溶解度 | Soluble in DMSO >10 mM |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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