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CHK1-IN-2
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
CHK1-IN-2图片
CAS NO:912367-45-4
包装与价格：
包装价格(元)
250mg电议
500mg电议

产品介绍
CHK1-IN-2是细胞周期检测点激酶(CHK1)的抑制剂，其IC50为6nM。
Cas No.912367-45-4
Canonical SMILESO=C(N)C1=C(SC(C2=CC=CC=C2)=C3)C3=C(N[C@@H]4[C@@H](C)NCCC4)N=C1
分子式C20H22N4OS
分子量366.48
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CHK1-IN-2 is a checkpoint kinase 1 (CHK1) inhibitor, with an IC50 of 6 nM.

CHK1-IN-2 is a checkpoint kinase 1 (CHK1) inhibitor, with an IC50 of 6 nM, which is a potential cancer therapeutic that can be utilized for enhancing the efficacy of DNA damaging agents[1].

[1]. Yang B, et al. Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) Inhibitors. J Med Chem. 2018 Feb 8;61(3):1061-1073.