您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Bz-RS-iSer(3-Ph)-OMe
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Bz-RS-iSer(3-Ph)-OMe
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bz-RS-iSer(3-Ph)-OMe图片
CAS NO:32981-85-4
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
100mg电议
250mg电议
500mg电议

产品介绍
Bz-RS-iSer(3-Ph)-OMe (compound 2) 是紫杉醇衍生物,在低细胞毒性下抑制 HSV 复制周期,阻断 Vero 细胞的有丝分裂,影响 M-MSV 诱导的肿瘤大小,并通过抑制 PHA 诱导的 T 淋巴细胞增殖而影响免疫应答。
Cas No.32981-85-4
别名(2R,3S)-3-苯甲酰氨基-2-羟基-3-苯基丙酸甲酯
Canonical SMILESO=C(OC)[C@H](O)[C@](NC(C1=CC=CC=C1)=O)([H])C2=CC=CC=C2
分子式C17H17NO4
分子量299.32
溶解度DMSO: 130 mg/mL (434.32 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Bz-RS-iSer(3-Ph)-OMe (compound 2), a Taxol derivative, inhibits HSV replication cycle at low cytotoxicity, blocks mitotic divisions of Vero cells, influences M-MSV induced tumor size and affects immune response by inhibiting PHA-induced T lymphocyte proliferation[1].

[1]. Krawczyk E, et al. Cytotoxic, antiviral (in-vitro and in-vivo), immunomodulatory activity and influence on mitotic divisions of three taxol derivatives: 10-deacetyl-baccatin III, methyl (N-benzoyl-(2'R,3'S)-3'-phenylisoserinate) and N-benzoyl-(2'R,3'S)-3'-phenylisoserine. J Pharm Pharmacol. 2005;57(6):791‐797.