Aminopurvalanol A 是一种有效的、选择性的和细胞渗透性的 Cyclins/Cdk 复合物抑制剂。 Aminopurvalanol A 优先靶向抑制癌细胞分化的 G2/M 期转变。 Aminopurvalanol A 通过抑制生理获能依赖性肌动蛋白聚合来抑制精子受精能力。
Cas No. | 220792-57-4 |
化学名 | (R)-2-((6-((3-amino-5-chlorophenyl)amino)-9-isopropyl-9H-purin-2-yl)amino)-3-methylbutan-1-ol |
Canonical SMILES | ClC1=CC(N)=CC(NC(N=C(N=C23)N[C@@H](CO)C(C)C)=C3N=CN2C(C)C)=C1 |
分子式 | C19H26ClN7O |
分子量 | 403.91 |
溶解度 | DMF: 50 mg/ml,DMF:PBS (pH 7.2) (1:5): 0.2 mg/ml,DMSO: 30 mg/ml,Ethanol: 10 mg/ml |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |