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TMPyP4 tosylate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TMPyP4 tosylate图片
CAS NO:36951-72-1
包装与价格:
包装价格(元)
10mM (in 1mL Water)电议
50mg电议

产品介绍
TMPyP4 tosylate (TMP 1363) 是一种四链体特异性配体,可抑制 G-四链体与 IGF-1 之间的相互作用。 TMPyP4 tosylate (TMP 1363) 是一种端粒酶抑制剂,在骨肉瘤细胞系中具有抗肿瘤作用。
Cas No.36951-72-1
别名TMPYP[=Α,Β,Γ,Δ-四(1-甲基吡啶嗡-4-基)卟吩对甲苯磺酸盐][铜和镁用超高灵敏分光光度试剂][用于以高效液相色谱金属同时测定],TMP 1363
分子式C72H66N8O12S4
分子量1363.6
溶解度≥ 55.6mg/mL in Water
储存条件Store at 2-8°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand, which inhibits the interaction between G-quadruplexes and IGF-1[1]. TMPyP4 tosylate (TMP 1363) is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines[2].

References:
[1]. Chen H, et al. Insuline-like growth factor type I selectively binds to G-quadruplex structures. Biochim Biophys Acta Gen Subj. 2019 Jan;1863(1):31-38.
[2]. Fujimori J, et al. Antitumor effects of telomerase inhibitor TMPyP4 in osteosarcoma cell lines. J Orthop Res. 2011 Nov;29(11):1707-11.