CAS NO: | 307986-98-7 |
包装: | 5mg |
市场价: | 1080元 |
Cas No. | 307986-98-7 |
Canonical SMILES | O=C(NC1=NN=NN1)C2=CC=C(CN(C3=CC=C(C4CCCCC4)C=C3)C(NC5=CC=CC(S(=O)(C)=O)=C5)=O)C=C2 |
分子式 | C29H31N7O4S |
分子量 | 573.67 |
溶解度 | DMSO: 250 mg/mL (435.79 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | NNC-0640 is a potent human G-protein-coupled glucagon receptor (GCGR) negative allosteric modulator (NAM) with an IC50 of 69.2 nM[1]. Human Glucagon Receptor [1] [1]. Zhang H, et al. Structure of the full-length glucagon class B G-protein-coupled receptor. Nature. 2017 Jun 8;546(7657):259-264. |