分子式: | C11H24BCl2N3O5 |
分子量: | 360.04 |
纯度: | >98% |
溶解性: | DMSO : < 1 mg/mL (insoluble or slightly soluble); H2O : ≥ 50 mg/mL (138.87 mM) |
存储: | 4℃,sealed storage, away from moisture |
研究领域: | Cancer |
Target: | IC50: 86 nM (Arginase 1), 296 nM (Arginase 2) |
描述: | CB-1158 dihydrochloride (INCB01158 dihydrochloride) is a potent and orally bioavailable inhibitor of arginase, with IC50s of 86 and 296 nM for recombinant human arginase 1 and 2, respectively. |