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(±)-Ibuprofen-d3
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(±)-Ibuprofen-d3图片
CAS NO:121662-14-4
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
50mg电议

产品介绍
布洛芬 D3 是一种氘标记的布洛芬。
Cas No.121662-14-4
别名氘代布洛芬,(±)-Ibuprofen-d3
Canonical SMILESOC(C(C1=CC=C(CC(C)C)C=C1)C([2H])([2H])[2H])=O
分子式C13H15D3O2
分子量209.3
溶解度DMF: >45 mg/ml,DMSO: >50 mg/ml,Ethanol: >60 mg/ml,PBS (pH 7.2): >2 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Ibuprofen-d3contains three deuterium atoms. It is intended for use as an internal standard for the quantification of ibuprofen by GC-or LC-mass spectrometry. Ibuprofen is a non-selective, reversible COX inhibitor. The IC50values for human recombinant COX-1 and -2 are 2.6 and 1.53 µM, respectively.1The Kivalue for ovine COX-1 and -2 is 9 µM.2

1.Barnett, J., Chow, J., Ives, D., et al.Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus systemBiochim Biophys. Acta.1209(1)130-139(1994) 2.Johnson, J.L., Wimsatt, J., Buckel, S.D., et al.Purification and characterization of prostaglandin H synthase-2 from sheep placental cotyledonsArch. Biochem. Biophys.324(1)26-34(1995)