CAS NO: | 484-14-0 |
包装: | 1mg |
市场价: | 1080元 |
Cas No. | 484-14-0 |
别名 | 7-羟基-8-(3-甲基-2-丁烯)-二氢苯并吡喃,Ostenol |
Canonical SMILES | O=C1C=CC2=CC=C(O)C(C/C=C(C)\C)=C2O1 |
分子式 | C14H14O3 |
分子量 | 230.26 |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Osthenol (Ostenol), a prenylated coumarin isolated from the dried roots of Angelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 µM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 µM and shows a high selectivity index for hMAO-A versus hMAO-B[1]. [1]. Baek SC, et al. Osthenol, a prenylated coumarin, as a monoamine oxidase A inhibitor with high selectivity. Bioorg Med Chem Lett. 2019;29(6):839-843. [2]. Liao ZC, et al. Zhongguo Zhong Yao Za Zhi. 2017;42(15):2999-3003. |