CAS NO: | 213382-49-1 |
包装 | 价格(元) |
25μg | 电议 |
50μg | 电议 |
100μg | 电议 |
250μg | 电议 |
Cas No. | 213382-49-1 |
别名 | (±)5,6-DiHETrE |
化学名 | (±)5,6-dihydroxy-8Z,11Z,14Z-eicosatrienoic acid |
Canonical SMILES | CCCCC/C=C\C/C=C\C/C=C\C[C@@H](O)[C@@H](O)CCCC(O)=O |
分子式 | C20H34O4 |
分子量 | 338.5 |
溶解度 | 50mg/mL in DMSO, 50mg/mL in DMF |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET by epoxide hydrolases. [1] 5(6)-DiHET can be used to quantify 5(6)-EET due to the conversion of 5(6)-EET to 5(6)-δ-lactone in solution. [2] 5(6)-DiHET activates large conductance calcium-activated potassium (BK) channels in smooth muscle cells from rat small coronary arteries. [3 It is a substrate for sheep seminal vesicle COX, producing 5,6-dihydroxy prostaglandin E1 and F1α metabolites in vitro. [4] 5(6)-DiHET levels decrease in plasma in a high-fat diet-induced rat model of hyperlipidemia.[5] Reference: |