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Esomeprazole potassium salt((S)-Omeprazole potassium)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Esomeprazole potassium salt((S)-Omeprazole potassium)图片
CAS NO:161796-84-5
包装与价格:
包装价格(元)
50mg电议
100mg电议

产品介绍
埃索美拉唑钾盐 ((S)-奥美拉唑钾) ((S)-奥美拉唑钾盐) 是一种有效的、具有口服活性的质子泵抑制剂,通过抑制胃壁细胞中的 H+、K+-ATPase 来减少酸分泌。
Cas No.161796-84-5
别名艾美拉唑钾盐,(S)-Omeprazole potassium salt; (-)-Omeprazole potassium salt
Canonical SMILESO=[S@](C1=NC2=CC=C(OC)C=C2[N-]1)CC3=NC=C(C)C(OC)=C3C.[K+]
分子式C17H18KN3O3S
分子量383.51
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Esomeprazole potassium salt is a proton pump inhibitor which reduces acid secretion through inhibition of the H+ / K+ ATPase in gastric parietal cells.IC50 value:Target: proton pumpEsomeprazole potassium salt is a proton pump inhibitor and gastric antisecretory agent indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagitis.

[1]. Thomas C Kupiec, Vasileios Aloumanis, Michel Ben, et al. Physical and Chemical Stability of Esomeprazole Sodium Solutions. Ann Pharmacother. September 2008 ,42 ( 9 ):1247-1251. [2]. Esomeprazole [3]. Sandstrom M, et al. Phase I, multicenter, randomized, open-label study evaluating the pharmacokinetics and safety profile of repeated once-daily doses of intravenous esomeprazole in children 0 to 17 years of age. Clin Ther. 2012 Aug;34(8):1828-38. [4]. Johnson TJ, Hedge DD. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59(14):1333-9.