CAS: | 867017-68-3 |
分子式: | C18H13ClF2N6O |
分子量: | 402.79 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Cardiovascular Disease |
Target: | IC50: 0.6 nM (Human ROCK-1), 1.1 nM (Human ROCK-2), 2.4 nM (Murine ROCK-2), 0.8 nM (Rat ROCK-2)[1] |
描述: | Azaindole 1 is a highly potent inhibitor of human ROCK-1 and ROCK-2, with IC50 of 0.6 and 1.1 nM, respectively, and also inhibits murine ROCK-2 or rat ROCK-2 with IC50 of 2.4 and 0.8 nM, respectively. |