| CAS： | 1190378-57-4 |
| 分子式： | C26H36N6O2 |
| 分子量： | 464.60 |
| 纯度： | ≥98% |
| 溶解性： | DMSO |
| 存储： | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
| 研究领域： | Inflammation/Immunology |
| Target： | IC50: 160 nM (IKKε, ATP), 19 nM (TBK-1, ATP), 45 nM (ULK1), 38 nM (ULK2) |
| 描述： | MRT67307 is a dual inhibitor of the IKKε and TBK-1, which mediates the phosphorylation of interferon regulatory factor 3 (IRF3), with IC50 values of 160 and 19 nM when assayed at 0.1 mM ATP in vitro, |
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