CAS: | 923359-38-0 |
分子式: | C14H16N2O2 |
分子量: | 244.29 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
研究领域: | Metbolic Disease |
Target: | IC50: 135 nM (ROCK-2), 102 nM (Human ROCK-2), 276 nM (Human ROCK-1)[1]Ki: 36 nM (Human ROCK-2), 41 nM (Rat ROCK-2)[1] |
描述: | SAR407899 is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Ki of 36 nM and 41 nM for human and rat ROCK-2, respectively. |