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Catharanthine hemitartrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Catharanthine hemitartrate图片
CAS NO:4168-17-6
包装:20mg
市场价:1134元

产品介绍
Catharanthine hemitartrate 是一种从马达加斯加长春花中分离的生物碱,抑制电压操作的 L 型 Ca2+ 通道,具有抗癌和降血压活性。
Cas No.4168-17-6
别名酒石酸长春质碱; (+)-3,4-Didehydrocoronaridine Tartrate
化学名(6R,6aR,9R)-methyl 7-ethyl-6,6a,9,10,12,13-hexahydro-5H-6,9-methanopyrido[1',2':1,2]azepino[4,5-b]indole-6-carboxylate 2,3-dihydroxysuccinate
Canonical SMILESCCC([C@]12[H])=C[C@@]3([H])C[C@]1(C(OC)=O)C4=C(C5=CC=CC=C5N4)CCN2C3.OC(C(O)=O)C(O)C(O)=O
分子式C25H30N2O8
分子量486.51
储存条件Store at -4℃, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Catharanthine Tartrate is an alkaloid isolated from Madagascar periwinkle, inhibits voltage-operated L-type Ca2+ channel, with anti-cancer and blood pressure-lowering activity[1].

References:
[1]. Jadhav A, et al. Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92.