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2-Amino-5-phenylpyridine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
2-Amino-5-phenylpyridine图片
CAS NO:33421-40-8
包装:500mg
市场价:450元

产品介绍
2-Amino-5-phenylpyridine是一种诱变的杂环芳族胺，是通过蛋白质中的苯丙氨酸热解形成的。2-Amino-5-phenylpyridine存在于烤沙丁鱼等食品中，并且具有潜在的致癌性。
Cas No.33421-40-8
别名2-氨基-5-苯基吡啶
Canonical SMILESNC1=NC=C(C2=CC=CC=C2)C=C1
分子式C11H10N2
分子量170.21
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2-Amino-5-phenylpyridine is a mutagenic heterocyclic aromatic amine that is formed by pyrolysis of phenylalanine in proteins. 2-Amino-5-phenylpyridine is in broiled sardines and is considered as potentially carcinogenic[1][2].

On the other hand, the chemical structure of 5-phenyl-2-pyridinamine (PPA) shows a great resemblance to the aminobiphenyls, another well known class of carcinogenic aromatic amines[2].

[1]. Dooley KL, et al. Comparative carcinogenicity of the food pyrolysis product, 2-amino-5-phenylpyridine, and the known human carcinogen, 4-aminobiphenyl, in the neonatal B6C3F1 mouse. Cancer Lett. 1988 Jul;41(1):99-103. [2]. Stavenuiter JF, et al. Syntheses of 5-phenyl-2-pyridinamine, a possibly carcinogenic pyrolysis product of phenylalanine, and some of its putative metabolites. Carcinogenesis. 1985 Jan;6(1):13-9.