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12-Ketodeoxycholic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
12-Ketodeoxycholic acid图片
CAS NO:5130-29-0
包装:100mg
市场价:3150元

产品介绍
12-Ketodeoxycholicacid是一种胆汁酸,是肾脏的代谢物。12-Ketodeoxycholicacid可以作为肾脏损伤的标志物。
Cas No.5130-29-0
别名胆酸杂质9
Canonical SMILESC[C@H](CCC(O)=O)[C@H]([C@]12C)CC[C@@]1([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC2=O
分子式C24H38O4
分子量390.56
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

12-Ketodeoxycholic acid is a bile acid, metabolite from kidney. 12-Ketodeoxycholic acid can be a detectable marker for evidence of kidney injury[1]

Bile acids are produced from conjugation of cholesterol and its incorporation in the bile by the liver for secretion in the intestine[1].

[1]. Chen H, et al. Metabolomics insights into activated redox signaling and lipid metabolism dysfunction in chronic kidney disease progression.Redox Biol. 2016 Dec;10:168-178.