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1,3-Dimethyluracil
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
1,3-Dimethyluracil图片
CAS NO:874-14-6
包装:500mg
市场价:450元

产品介绍
1,3-Dimethyluracil是由尿嘧啶衍生而来的嘧啶。1,3-Dimethyluracil偶见于人尿中。1,3-Dimethyluracil对hCAI和hCAII有抑制活性，Ki分别为316.2μM和166.4μM。
Cas No.874-14-6
别名1,3-二甲基脲嘧啶
Canonical SMILESCN1C=CC(=O)N(C)C1=O
分子式C6H8N2O2
分子量140.14
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

1,3-Dimethyluracil is a pyrimidone derives from a uracil. 1,3-Dimethyluracil found occasionally in human urine. 1,3-Dimethyluracil shows inhibition activity against hCA I and hCA II (human carbonic anhydrase) with Ki of 316.2 μM and 166.4 μM, respectively[1][2].

[1]. Stoessel D, et al. Promising Metabolite Profiles in the Plasma and CSF of Early Clinical Parkinson's Disease. Front Aging Neurosci. 2018 Mar 5;10:51. [2]. GÜney M, et al. Synthesis and carbonic anhydrase inhibitory properties of novel uracil derivatives. Bioorg Med Chem Lett. 2015 Aug 15;25(16):3261-3.